Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Low Molecular Weight Heparins (LMWH)
- Target
- LMWH
- Molecular classification
- Anticoagulant, Heparin derivative, Polysaccharide
01
Overview
Low molecular weight heparins (LMWHs) are a class of anticoagulant medications derived from unfractionated heparin (UFH) by chemical or enzymatic depolymerization. They consist of shorter polysaccharide chains, with an average molecular weight typically between 4,000 and 6,000 Daltons. LMWHs are primarily used for the prevention and treatment of thromboembolic disorders.
- Other names
- EnoxaparinDalteparinTinzaparinCertoparinNadroparinParnaparinReviparin
02
Mechanism of action
Activation of antithrombin III, leading to inhibition of factor Xa in the coagulation cascade. Reduced ability to inhibit thrombin (factor IIa) compared to UFH.
03
Biological functions
AnticoagulationInhibition of Factor XaActivation of Antithrombin III
04
Disease associations
Thromboembolic disordersDeep Vein Thrombosis (DVT)Pulmonary Embolism (PE)Myocardial InfarctionAcute Coronary SyndromesUnstable Angina
05
Safety considerations
Heparin-induced thrombocytopenia (HIT)Renal impairmentBleeding riskOsteoporosis/osteopenia (lower risk than UFH, but still a concern)
06
Interacting drugs
Lovenox (Enoxaparin)
6 more in the full profile.
Beyond the preview
Go deeper on Low Molecular Weight Heparins (LMWH).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Low Molecular Weight Heparins (LMWH).