Lymphocyte infiltration

**Lymphocyte infiltration** refers to the process by which lymphocytes, a type of white blood cell involved in adaptive and innate immunity, migrate from the bloodstream into tissues—often in response to infection, inflammation, or tumor presence[1][3]. This phenomenon is observed in various pathological contexts including cancer (where it is termed "tumor-infiltrating lymphocytes" or TILs), autoimmune diseases, and chronic inflammatory conditions. The presence and extent of lymphocyte infiltration are often used as indicators of immune activity within tissues. For example, high levels of TILs within tumors are generally associated with better clinical outcomes after surgery or immunotherapy[2]. However, "lymphocyte infiltration" itself is not a specific molecule or receptor but rather describes an immunological process involving multiple cell types and signaling pathways. > There is something incorrect about this target entry: "Lymphocyte infiltration" does not refer to a single molecule or receptor but rather an immunopathological process involving many different molecules and cells. It cannot be considered a canonical therapeutic target like an enzyme or receptor would be[1][2][3].

Other names

Lymphocyte infiltrationCellular infiltration (context-dependent)