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Lymphocyte surface proteins are a diverse group of molecules expressed on the plasma membrane of lymphocytes, including T cells, B cells, and innate lymphoid cells. These proteins play critical roles in immune recognition, cell signaling, migration, and intercellular communication. They are essential for adaptive immunity and are clinically relevant in disease and immunotherapy. Examples include immunoreceptors like TCR and BCR, co-receptors like CD4 and CD8, adhesion molecules like L-selectin and integrins, regulatory proteins like BTLA, and membrane organizers like tetraspanins and galectins.
Varies depending on the specific protein. Examples include blocking receptor-ligand interactions, modulating signaling pathways, and promoting cell death.
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