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Lymphocyte surface proteins are a diverse group of molecules expressed on the plasma membrane of lymphocytes, including T cells, B cells, and innate lymphoid cells. They are critical for immune recognition, cell signaling, migration, adhesion, and intercellular communication. These proteins serve as targets for therapeutic intervention in a range of diseases, including cancer, autoimmune disorders, and immunodeficiencies.
Varies depending on the specific protein. Examples include: receptor blockade, co-stimulation modulation, signal transduction inhibition, cell depletion (via antibody-dependent cell-mediated cytotoxicity or complement-dependent cytotoxicity).
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