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The LYR motif containing 9 pseudogene (ENSG00000271526) is a non-protein coding pseudogene annotated in the human genome. It is related to the LYRM protein family, which includes mitochondrial proteins characterized by a conserved leucine-tyrosine-arginine motif and typically are small, positively charged, and participate in assembly or function of the mitochondrial electron transport chain. LYRM9, the canonical protein-coding gene, has links to mitochondrial localization and rare disease associations. Pseudogenes generally do not encode functional proteins, though there is increasing evidence some may have regulatory RNA functions; however, no functional protein, therapeutic targeting, or biological relevance is established for this specific pseudogene. Its status as a "target" for therapy or pharmacology is unsupported, and its entry as a therapeutic or receptor molecule is incorrect.
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