Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Lysine Acetyltransferase 6A (KAT6A)
- Target
- KAT6A
- Molecular classification
- Enzyme, Histone modification, Lysine acetyltransferase, Transcription factor
01
Overview
Lysine Acetyltransferase 6A (KAT6A) is an enzyme that functions as a histone acetyltransferase, playing a key role in chromatin remodeling and gene transcription. It is involved in various developmental processes and can act as both an oncogene and tumor suppressor depending on context. Mutations in KAT6A cause Arboleda-Tham syndrome, and aberrant expression is linked to various cancers and cognitive impairment.
- Other names
- MOZMYST3
02
Mechanism of action
Inhibition of KAT6 family enzymes (competitive with acetyl-CoA)
03
Biological functions
Histone acetylationTranscriptional regulationStem cell developmentChromatin remodelingRegulation of cell cycle progressionDNA repairMetabolismMitosisSignal transductionProtein foldingAutophagy
04
Disease associations
Arboleda-Tham SyndromeAcute Myeloid LeukemiaOvarian CancerCognitive ImpairmentLung CancerBreast Cancer
05
Interacting drugs
WM‑1119
1 more in the full profile.
Beyond the preview
Go deeper on Lysine Acetyltransferase 6A (KAT6A).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Lysine Acetyltransferase 6A (KAT6A).