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Target intelligence / Profile preview
Lysozyme
- Molecular classification
- Enzyme, Glycoside Hydrolase
01
Overview
Lysozyme is a hydrolytic enzyme and a key component of the innate immune system, found in various animal and plant sources. It functions as an antimicrobial agent by degrading bacterial cell walls, and it also plays a role in modulating immune responses. Its structure and mechanism have been extensively studied, making it a model enzyme in biochemistry. Lysozyme has applications in food preservation, pharmaceuticals, and potentially in cancer therapy due to its immunomodulatory properties.
- Other names
- MuramidaseN-acetylmuramide glycanhydrolase
02
Mechanism of action
Lysozyme hydrolyzes the β-(1,4)-glycosidic bond between N-acetylmuramic acid (NAM) and N-acetylglucosamine (NAG) in peptidoglycan, leading to bacterial cell wall lysis.
03
Biological functions
Antimicrobial defenseInnate immunityHydrolysis of peptidoglycanImmunomodulation
04
Disease associations
InfectionCancer (potential immunomodulatory role)Epithelial tissue maintenance
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