macrophage stimulating 1 pseudogene 2 (MST1P2)

macrophage stimulating 1 pseudogene 2 (MST1P2) is classified as a pseudogene, meaning it is an inactive segment of DNA that is similar to a functional gene but does not encode a functional protein. It is related to the functional macrophage stimulating 1 (MST1) gene, which codes for the cytokine MSP, but MST1P2 does not encode a protein product and has no known biological or disease function as a protein, receptor, or therapeutic target[1][4][7][8][14]. MST1P2 is not an active protein or receptor, but a pseudogene, meaning the information does not pertain to a therapeutic target. The related active protein is MSP, encoded by MST1, which is a cytokine involved in macrophage signaling[6][12]. There are no drugs, mechanisms of action, or known biomarker or safety issues associated with the pseudogene MST1P2[4][14]. Claims found in some databases that MST1P2 might play a regulatory RNA role (as in cancer progression via sponging microRNA) are not equivalent to it being a classic protein therapeutic target or receptor[8]. If you are seeking information about the functional target in the macrophage stimulating protein pathway, you should look for macrophage stimulating 1 (MST1) or macrophage stimulating 1 receptor (MST1R, also known as RON), not MST1P2[11][12][13]. Summary statement: MST1P2 is a pseudogene, not a receptor or enzyme, with no established role as a therapeutic target[4][7][14]. Any apparent confusion with the actual targetable protein (MSP, MST1) should be clarified for downstream structured data collection.

Other names

MSPL-2MSPL2MSTP2