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MAD1 mitotic arrest deficient-like 1 pseudogene

Molecular classification: Other (pseudogene)

Overview

ENSG00000227755 refers to the MAD1 mitotic arrest deficient-like 1 pseudogene, a *pseudogene* related to the MAD1L1 gene. Unlike MAD1L1, which encodes a core component of the mitotic spindle assembly checkpoint and plays essential roles in mitosis and tumor suppression, this pseudogene does not encode a functional protein. As such, it is not considered a therapeutic target and has no known direct biological function or disease association[6]. Key distinction: The *functional protein-coding gene* is MAD1L1 (mitotic arrest deficient 1-like 1), an important cell cycle regulator involved in spindle checkpoint control. *ENSG00000227755* is a related pseudogene and does not produce a functional protein product, nor is it itself targeted pharmacologically[6]. If you are interested in the functional target (the protein), refer to *MAD1L1* (Ensembl ID: ENSG00000002822)[6].

Other names: MAD1 Mitotic Arrest Deficient-Like 1 (Yeast) Pseudogene

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