MADCAM1 antisense RNA 1 (MADCAM1-AS1)

MADCAM1 antisense RNA 1 (MADCAM1-AS1) is a long non-coding RNA gene transcribed from the opposite strand of the MADCAM1 region. Unlike MADCAM1, which encodes an endothelial adhesion protein involved in mucosal immunity, MADCAM1-AS1 does not encode a protein and has no confirmed therapeutic target status. Its biological function, disease relevance, and utility as a drug target or biomarker remain uncharacterized in current scientific resources. Key clarifications: MADCAM1-AS1 is not a protein, not a receptor, not an enzyme, and does not have established therapeutic target status. The entry may be based on a misunderstanding or is incomplete; MADCAM1 (the protein-coding gene) is a completely different, well-characterized therapeutic target implicated in inflammation and is a target of drugs such as ontamalimab, but MADCAM1-AS1 is not. If you intended information on the protein-coding MADCAM1 ("Mucosal vascular addressin cell adhesion molecule 1"), that molecule is a well-established therapeutic target, with numerous drugs and disease associations. In contrast, MADCAM1-AS1 is a non-coding RNA with limited characterization and currently not recognized as a druggable molecular target.

Other names

MADCAM1-AS1