Maestro heat-like repeat-containing protein family member 2B (MROH2B)

Maestro heat-like repeat-containing protein family member 2B (MROH2B) is a protein encoded by the human MROH2B gene. It is predicted to be involved in protein kinase A signaling and has been implicated in the process of sperm capacitation, a physiological change that sperm undergo to become capable of fertilizing an egg. The protein colocalizes with PRKACA and TCP11 in the acrosome and tail regions of spermatozoa, suggesting a functional role in sperm structure or signaling. MROH2B is associated with certain complex diseases such as polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract, but there is no evidence that it acts as a direct therapeutic target, receptor, enzyme, transporter, or classical drug discovery target in current biomedical literature[1][3][5][10][12][13].

Other names

Maestro heat like repeat family member 2BHEATR7B2SPIFDKFZp781F0822FLJ40243Sperm PKA-interacting factormaestro heat-like repeat-containing protein family member 2BHEAT repeat family member 7B2HEAT repeat-containing protein 7B2