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Target intelligence / Profile preview
Maestro heat-like repeat family member 2A (MROH2A)
- Target
- MROH2A
- Molecular classification
- Other: HEAT repeat-containing protein (contains HEAT domains), Protein coding gene
01
Overview
Maestro heat-like repeat family member 2A (MROH2A) is a protein-coding gene encoding a protein that contains HEAT domains, a type of structural repeat frequently involved in protein-protein interactions and intracellular transport. The precise function, biological role, and structural details of MROH2A remain uncharacterized. Although variants in MROH2A have been noted in association with congenital myasthenic syndrome, no broader disease associations, mechanisms, or therapeutic targeting roles are established. The protein is cataloged in major genetic reference resources, but as of current knowledge, it is not considered a major drug target nor has its function been elucidated[2][3][6][7].
- Other names
- HEATR7B1Maestro heat-like repeat-containing protein family member 2AHEAT repeat-containing protein 7B1HEAT repeat containing 7B1
02
Mechanism of action
None described, because no drugs are reported to target MROH2A
03
Biological functions
Unknown. The specific biological function of MROH2A has not been characterized and is not described in gene/protein databases
04
Disease associations
Other: Association reported with Congenital myasthenic syndromeNo well-established disease roles based on current data
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