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MAGEA8 antisense RNA 1 (MAGEA8-AS1)

Target: MAGEA8-AS1
Molecular classification: Long non-coding RNA (lncRNA), Antisense RNA

Overview

MAGEA8 antisense RNA 1 (MAGEA8-AS1) is a long non-coding RNA (lncRNA) gene located on chromosome X and transcribed antisense to the MAGEA8 gene. It is also referenced as RP5-869M20.2. MAGEA8-AS1 is classified as an antisense non-coding RNA; such RNAs can modulate gene expression at the transcriptional or post-transcriptional level but the precise biological function of MAGEA8-AS1 is currently unknown. There is a reported association of this lncRNA with muscular dystrophy, though additional clinical or mechanistic characterization is lacking. No evidence currently supports its role as a therapeutic target, biomarker, or direct involvement in drug interactions.

Other names: RP5-869M20.2

Biological functions

Regulation of gene expression (possible/putative based on the role of antisense lncRNAs)Other

Disease associations

Muscular dystrophy (reported association, but mechanism or significance is unclear)

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