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Magnesium ion homeostasis regulator

Molecular classification
Other
01

Overview

The term **"Magnesium ion homeostasis regulator"** is not the canonical name for a single, well-defined molecular target. Instead, it refers broadly to any protein or system involved in maintaining the balance of magnesium ions (Mg2+) within cells and across tissues. Magnesium homeostasis involves multiple proteins, including channels such as MgtE (in prokaryotes), TRPM6 and TRPM7 (in mammals), transporters like SLC41 family members, and regulatory pathways that control import and export of Mg2+[1][3]. These proteins play essential roles in processes such as enzyme activation, ATP utilization, nucleic acid stability, neuromuscular excitability, and signal transduction[1][3][4]. Disruption of these systems can lead to disorders related to abnormal magnesium levels but there is no single molecule officially named "Magnesium ion homeostasis regulator." Therefore, this entry does not correspond to a specific therapeutic target or receptor. In summary, "Magnesium ion homeostasis regulator" is too generic; it describes a physiological function rather than an individual molecular entity. For structured data purposes or drug discovery efforts, more precise targets should be specified—such as "Transient receptor potential cation channel subfamily M member 6 (TRPM6)" or "MgtE magnesium transporter"[1][3].

02

Biological functions

Regulation of magnesium ion (Mg2+) concentrationCellular magnesium transportMaintenance of cellular and systemic Mg2+ balance
03

Disease associations

Other (abnormalities in Mg2+ homeostasis are implicated in various diseases, but "Magnesium ion homeostasis regulator" is not a specific disease target)

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