Mago nashi homolog B pseudogene

Mago nashi homolog B pseudogene (ENSG00000248891, LOC105379196) is annotated in the genome as a pseudogene related to MAGOHB (mago nashi homolog B), which itself is a protein-coding gene involved in mRNA splicing and nonsense-mediated decay as a core component of the exon junction complex[5]. As a pseudogene, it does not encode a functional protein and is not considered a druggable target, receptor, enzyme, or transporter. No biological functions, disease roles, drug interactions, or therapeutic relevance are described, and there is no evidence supporting its use as a biomarker or the presence of specific safety concerns. The inclusion of "pseudogene" in the name indicates it is nonfunctional at the protein level, and therefore it is not a valid target for therapeutic intervention. Notes on correctness and target status: - The entity described by ENSG00000248891/LOC105379196 is a pseudogene, not an active, transcribed, or translated receptor, enzyme, transporter, or otherwise druggable biological target[5]. - The actual protein-coding, therapeutically relevant genes are MAGOH and MAGOHB, not this pseudogene[4][5]. - Mark the entry as is_incorrect: true, since pseudogenes are typically excluded from lists of functional molecular drug targets.

Other names

LOC105379196ENSG00000248891mago-nashi homolog B pseudogene