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Major facilitator superfamily domain-containing protein 11 (MFSD11)

Target: MFSD11
Molecular classification: Transporter (major facilitator superfamily/unc-93 family)

Overview

Major facilitator superfamily domain-containing protein 11 (MFSD11) is a membrane protein believed to function as a transporter within the major facilitator superfamily, specifically in the unc-93 family, and is abundantly expressed in the brain. It is predicted to play a role in cellular response to food and starvation, and has been associated in some studies with energy homeostasis. Disease associations include several forms of leukemia, but it is not currently an established therapeutic target[1][2][4][6].

Other names: UNC93-like protein MFSD11ETFLJ22196FLJ20226protein ET

Biological functions

Response to foodResponse to starvationEnergy homeostasisPutative transporter activity

Disease associations

Atypical chronic myeloid leukemiaAcute myeloid leukemia (Bcr-Abl1 negative)

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