Male-specific lethal 3 homolog 2

MSL complex subunit 3B (MSL3B) refers to a genomic locus typically classified as a pseudogene or a predicted protein in humans, with no well-established protein product or function. The canonical "male-specific lethal 3" protein (MSL3) in *Drosophila* is a member of the MSL complex responsible for X-chromosome dosage compensation and acts via specific chromodomain and histone interaction[1][2]. In humans, MSL3 is conserved and participates in histone modification complexes, but "MSL3B" denotes a paralog or pseudogene without clear functional evidence. As such, MSL3B is not recognized as a therapeutic target or a defined member of classical druggable protein families. Key points: - The main functional protein in the dosage compensation complex is MSL3, not "MSL3B". - The "MSL3B" locus in humans is typically annotated as a pseudogene or predicted protein, not a validated coding gene or receptor. - There is no evidence that "MSL3B" is involved in disease, encodes a functional protein, or is a drug target. References to MSL3B often reflect annotation or computational prediction rather than validated biology or pharmacology[1][2].

Other names

MSL3L2MSL3P1MSL3BMSL3-like 2male-specific lethal-3 protein-like 2male-specific lethal 3 homolog pseudogene 1MSL3 complex subunit 3B