Target intelligence / Profile preview

Streptococcus pneumoniae Protein Antigen SP2108 (SP2108)

Target: SP2108
Molecular classification: Protein, Antigen

Overview

SP2108 is a conserved and highly immunogenic maltose-binding protein from Streptococcus pneumoniae. It is a promising vaccine candidate due to its high conservation across global isolates and its ability to induce protective immune responses, particularly via TLR2 activation and Th17/IL-17A-mediated immunity. It has shown potential in reducing pneumococcal colonization in clinical trials and is considered a broad-spectrum vaccine target.

Other names: Maltose-binding proteinSP_2108

Mechanism of action

N/A

Biological functions

Carbohydrate transportCarbohydrate metabolismImmune response

Disease associations

InfectionPneumococcal disease

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