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Target intelligence / Profile preview
MAN1B1 divergent transcript (MAN1B1-DT)
- Target
- MAN1B1-DT
- Molecular classification
- Other, long non-coding RNA (lncRNA), antisense RNA
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Overview
MAN1B1 divergent transcript (MAN1B1-DT) is a long non-coding RNA gene located on chromosome 9 in humans, positioned head-to-head with the protein-coding MAN1B1 gene. The transcript is described in genomic annotation resources (HGNC, Alliance of Genome Resources) as "MAN1B1 divergent transcript," with MAN1B1-AS1 and "MAN1B1 antisense RNA 1 (head to head)" recognized as alternative names[2][4]. Currently, there is no experimentally-confirmed function, disease linkage, or protein product attributed to MAN1B1-DT; this distinguishes it from the unrelated protein-coding gene MAN1B1, which encodes a glycosyl hydrolase enzyme involved in glycoprotein quality control in the ER[1][3]. There is no evidence to support MAN1B1-DT as a therapeutic target, biomarker, or drug interaction molecule.
- Other names
- MAN1B1-AS1MAN1B1 antisense RNA 1 (head to head)MAN1B1-DT
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