MAN2A1 divergent transcript (MAN2A1-DT)

MAN2A1-DT (MAN2A1 divergent transcript) is a non-coding RNA transcript arising from the *MAN2A1* gene region, likely transcribed from the opposite DNA strand in a bidirectional promoter context[1][5]. Divergent transcripts (often classified as long non-coding RNAs) are frequently observed from active promoters and may play regulatory roles in gene expression, though most have not been functionally characterized[5]. There is no evidence that MAN2A1-DT itself encodes a functional protein or serves as a validated molecular target for drugs or therapeutic intervention. If you intended the protein-coding enzyme **alpha-mannosidase 2** (encoded by *MAN2A1*), that is a functionally distinct entity and should be queried as “Mannosidase alpha class 2A member 1 (MAN2A1)” instead[2][3].