Target intelligence / Profile preview

Mannan endo-1,4-beta-mannosidase

Molecular classification
Enzyme, Glycoside hydrolase, Carbohydrate-active enzyme
01

Overview

Mannan endo-1,4-beta-mannosidase is an enzyme that catalyzes the random (endo-type) hydrolysis of (1→4)-beta-D-mannosidic linkages in the backbone of plant-derived polysaccharides such as mannans, galactomannans, and glucomannans. It is classified under EC 3.2.1.78 and is a key member of the glycoside hydrolase family involved in the degradation of hemicellulosic components in plant cell walls. The enzyme is widely distributed in bacteria, fungi, and plants, and has significant roles in biotechnology, particularly for applications in biomass conversion, food and feed processing, paper and pulp industries, and the production of biofuels. Mannan endo-1,4-beta-mannosidase is not recognized as a human therapeutic target, but is of commercial and industrial importance due to its ability to break down complex carbohydrates into fermentable sugars.

Other names
Endo-1,4-beta-mannanaseEndo-beta-1,4-mannaseBeta-mannanase BBeta-1,4-mannan 4-mannanohydrolaseEndo-beta-mannanaseBeta-D-mannanase1,4-beta-D-mannan mannanohydrolase
02

Mechanism of action

Hydrolytic cleavage of internal (1→4)-beta-D-mannosidic linkages in mannan-type polysaccharides, producing smaller oligosaccharides

03

Biological functions

Hydrolysis of beta-1,4-mannosidic linkages in mannans, galactomannans, and glucomannansCell wall degradation in plant biomassOligosaccharide productionBiopolymer breakdown
04

Disease associations

Other (used indirectly in industrial and biotechnological processes, not primarily associated with human disease)

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