MANSC domain-containing protein 4 (MANSC4)

MANSC domain-containing protein 4 is a human protein of previously uncharacterized function, encoded by the MANSC4 gene on chromosome 12. It contains a MANSC domain, which is structurally associated with transmembrane regions and signal peptides, and is predicted to participate in the negative regulation of serine-type endopeptidases and in development of epidermal and epithelial tissues. Its role in disease and cellular processes is largely unknown, with only speculative links to conditions such as Eiken syndrome via genetic association, and it has no defined role in signaling, transport, or as a therapeutic target. There is currently no direct evidence linking MANSC4 to major pathological processes, therapeutic interventions, or known drugs, nor is it used as a clinical biomarker. No functional studies or mechanistic disease association data are present in the available literature.

Other names

MANSC4MANSC domain-containing protein 4ENSP00000370673MANS4_HUMAN