Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
MAP6 domain-containing protein 1 (MAP6D1)
- Target
- MAP6D1
- Molecular classification
- Other (belongs to the microtubule-associated protein family, specifically the STOP protein family)
01
Overview
MAP6 domain-containing protein 1 (MAP6D1) is a microtubule-associated protein highly similar to the STOP protein family, expressed in the human brain, including the spinal cord, and implicated in the stabilization and trafficking of microtubules, especially under conditions of stress such as cold or drug exposure[4][5]. Its functional domains are homologous to those found in other MAP6 family proteins, including calmodulin-binding motifs and stabilization modules, enabling it to regulate microtubule architecture in neurons. While MAP6D1 shares functional similarities and high sequence homology with canonical MAP6 proteins, there is limited evidence for a direct role in human disease or as a therapeutic drug target[4][2][3][5].
- Other names
- MAP6D1SL21FLJ1274821 kDa STOP-like proteinSTOP-Like protein 21 kDMAPO6D1MAP6 domain containing 1MAP6 domain-containing protein 1
02
Biological functions
Microtubule stabilizationRegulation of microtubule dynamics, including protection against cold- and drug-induced depolymerizationPotential roles in neuroreceptor homeostasis, endocytosis, nuclear function, and signal transduction
03
Disease associations
Other (no direct associations with major disease classes such as cancer, neurodegeneration, or cardiovascular disease have been reported for MAP6D1 specifically; related MAP6 family members have shown neurological importance)
04
Safety considerations
None known
05
Interacting drugs
None known
06
Biomarkers
None known
Beyond the preview
Go deeper on MAP6 domain-containing protein 1 (MAP6D1).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on MAP6 domain-containing protein 1 (MAP6D1).