Target intelligence / Profile preview

MAP7 antisense RNA 1 (MAP7-AS1)

Target
MAP7-AS1
Molecular classification
Long non-coding RNA (lncRNA), Antisense RNA
01

Overview

MAP7 antisense RNA 1 (MAP7-AS1) is a long non-coding RNA found at locus chr6:136550661-136552554 in the human genome. It is transcribed antisense to the MAP7 (Microtubule Associated Protein 7) gene but does not encode a protein product. Antisense lncRNAs such as MAP7-AS1 can regulate gene expression through cis- or trans-acting mechanisms, typically by influencing the transcription, splicing, or stability of sense transcripts. No direct disease associations, drug interactions, or validated biomarker roles are currently reported for MAP7-AS1. MAP7-AS1 should not be confused with the protein-coding MAP7 gene. The biological functions of antisense lncRNAs are sometimes inferred from studies on similar RNAs, and specific functional data for MAP7-AS1 in disease or as a drug target are currently lacking.

02

Mechanism of action

Not applicable (No drugs directly targeting MAP7-AS1 are reported. Antisense RNAs can regulate genes in cis or trans by transcription- or RNA-dependent mechanisms, but specific mechanisms for MAP7-AS1 are not described in available sources)

03

Biological functions

Regulation of gene expressionPossible involvement in modulating the expression of the MAP7 gene or other local genes (inferred from the typical functions of antisense lncRNAs)
04

Disease associations

Not directly linked to specific diseases to date, but lncRNA antisense transcripts (in general) have been implicated in cancer, neurodegenerative disease, and other pathological conditions

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