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Target intelligence / Profile preview
MAP9 antisense RNA 1 (MAP9-AS1)
- Target
- MAP9-AS1
- Molecular classification
- Long non-coding RNA, Antisense RNA
01
Overview
MAP9 antisense RNA 1 (MAP9-AS1) is a long non-coding RNA (lncRNA) transcribed antisense to the MAP9 gene, located on chromosome 4 (155,173,525-155,381,694 on the forward strand)[7][1]. Antisense lncRNAs such as MAP9-AS1 are typically involved in regulating the expression of their neighboring “sense” genes—the process can involve mechanisms like chromatin modification, recruitment of epigenetic regulators, or modulation of mRNA stability[2][4][6]. While other antisense lncRNAs have documented involvement in cancer, inflammation, and cell proliferation, there is currently no published experimental evidence regarding the biological function or disease association specific to MAP9-AS1. MAP9-AS1 is not a protein, receptor, enzyme, or conventional drug target; rather, it is a regulatory RNA, and thus, is not considered a therapeutic target itself[1][7]. Antisense lncRNAs as a group are subjects of ongoing research for potential roles as biomarkers and therapeutic targets, but MAP9-AS1 specific roles and applications remain uncharacterized as of current data[2][6][9].
- Other names
- MAP9-AS1MAP9 antisense RNA 1
02
Biological functions
Regulation of gene expressionChromatin modificationPotential transcriptional regulation in cis or transEpigenetic regulation
03
Disease associations
Other (general lncRNAs have been studied for roles in cancer, but specific evidence for MAP9-AS1 is not available as of current data)
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