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Target intelligence / Profile preview
MAPK regulated corepressor interacting protein 2 (MCRIP2)
- Target
- MCRIP2
- Molecular classification
- Other (RNA-binding protein, LIM domain protein)
01
Overview
MAPK regulated corepressor interacting protein 2 (MCRIP2) is a cytoplasmic and nuclear protein characterized by RNA binding activity and LIM domains. It is implicated in transcriptional regulation and skeletal muscle differentiation, notably influencing gene promoters tied to muscle development (e.g., MyoD1) and copper homeostasis. MCRIP2 is regulated by copper levels and is required for normal muscle cell differentiation, but has not been established as a therapeutic target, receptor, or enzyme. While it plays important roles in muscle development and metal metabolism, there are currently no drugs or biomarker roles associated with MCRIP2, and it is not linked to specific human diseases.
- Other names
- MAPK regulated corepressor interacting protein 2MCRIP2C16orf14FAM195AMGC15416Protein FAM195Ac349E10.1family with sequence similarity 195 member A
02
Biological functions
RNA bindingtranscriptional regulationmetal (copper) homeostasisskeletal muscle differentiationnuclear/cytoplasmic protein localization
03
Disease associations
Other (no direct, confirmed link to major disease categories in public sources)
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