Marker of proliferation Ki-67 pseudogene

Marker of proliferation Ki-67 pseudogene (Gene ID: ENSG00000273763) is a nonfunctional DNA sequence with high homology to the canonical *MKI67* gene. Unlike the functional *MKI67* gene—which encodes the proliferation marker protein Ki-67 used in pathology as a marker for cell proliferation in cancer diagnostics—this pseudogene does not encode a protein and has no established biological, pathological, or therapeutic function[1][2][4]. Pseudogenes may be transcribed at low levels, but their transcripts are usually non-functional and lack the regulatory elements or coding capacity to produce an active protein[2][4]. This entry should not be considered a therapeutic target. Key distinguishing point: - *Marker of proliferation Ki-67 pseudogene* should not be confused with the canonical MKI67 gene, which is a functional proliferation biomarker[3][5]. - Pseudogenes like this can complicate genetic studies due to their sequence similarity with the functional gene but lack a protein product or direct biological function[4].

Other names

MKI67 pseudogeneMKI67P