MAS related GPR family member X10 pseudogene (MRGPRX10P)

MAS related GPR family member X10 pseudogene (MRGPRX10P) is annotated as a pseudogene, not an active gene coding for a functional protein or receptor. The MRGPR (MAS-related G protein-coupled receptor) family includes both functional receptors and pseudogenes; in humans, there are eight MRGPR genes with intact coding sequences and a number of pseudogenes[1][3]. Pseudogenes like MRGPRX10P are typically nonfunctional genomic sequences resembling functional genes but lacking protein-encoding capability and are not considered therapeutic targets. No biological roles, disease associations, or targeting drugs are described for this entity in the available literature[1][3][4]. Key context: - The main functional human MRGPR 'X' cluster receptors are MRGPRX1, MRGPRX2, MRGPRX3, and MRGPRX4[2][4]. - The majority of MRGPR family members outside these four, including MRGPRX10P, are pseudogenes with no known molecular function or relevance as drug targets[1][3][4]. - MRGPRX10P appears to be a misapplied or erroneous name; it is not referenced as a standard or known active GPCR in receptor databases or the published literature[1][3][4]. Summary: MRGPRX10P is a pseudogene and not a functional therapeutic target. The main, functional MRGPRX receptors are X1–X4; "X10" is not a recognized functional member or abbreviation of this family, indicating either an outdated annotation or a database error.

Other names

MAS related GPR family member X1 pseudogeneMAS-related GPR, member X1 pseudogeneMRGPRX10P