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Target intelligence / Profile preview
MAS related GPR family member X8, pseudogene (MRGPRX8P)
- Target
- MRGPRX8P
- Molecular classification
- Other (Pseudogene), G protein-coupled receptor pseudogenes
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Overview
MAS related GPR family member X8, pseudogene (MRGPRX8P) is classified as a pseudogene, meaning it is a non-functional segment of DNA resembling a gene from the mas-related G protein-coupled receptor family[1][5]. There is no evidence that MRGPRX8P encodes a functional protein, and it is not considered a receptor, enzyme, or other druggable target. As a member of the MRGPR gene family, its functional gene relatives (such as MRGPRX2) do act as receptors mediating sensory signaling (itch and pain)[2], but MRGPRX8P itself does not produce a functional product, has no established biological function or disease association, and is not pursued in pharmacological research.
- Other names
- MAS related GPR family member X2 pseudogeneMRGPRX8P
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