MAS related GPR family member X9 pseudogene (MRGPRX9P)

MAS related GPR family member X9 pseudogene (MRGPRX9P) is classified as a pseudogene related to the MAS-related G protein-coupled receptor family. Unlike its functional relatives in the MRGPRX (X1-X4) cluster, which are true GPCRs mediating neuro-immune functions, pain, and itch, this locus does not encode a functional protein. The MRGPR family contains several pseudogenes, especially in both the human and mouse genomes, lacking intact open reading frames[1][5]. As a pseudogene, MRGPRX9P is not considered a therapeutic target and has no known biological functions, disease associations, or interacting drugs. There is some confusion in alias usage as this locus has also been referred to as 'MAS related GPR family member X3 pseudogene,' but both forms refer to nonfunctional genetic loci, not expressed proteins. Key details: - This gene is a **pseudogene**—it does not encode a functional protein and is not a therapeutic target[1][5]. - There are **no reported biological functions, disease roles, drug interactions, or biomarkers** for MRGPRX9P. - Functional MRGPRX members (such as MRGPRX1–X4) are GPCRs with important roles in neuro-immune signaling, but this locus is **non-coding**[1][2][5]. - The naming (MRGPRX9P, MRGPRX3 pseudogene) **reflects a nonfunctional gene** within the larger MRGPRX family.

Other names

MAS related GPR family member X3 pseudogeneMRGPRX9P