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MAS1L pseudogene 1 (MAS1LP1)

Target
MAS1LP1
Molecular classification
Other (Pseudogene)
01

Overview

MAS1L pseudogene 1 (MAS1LP1) is classified as a pseudogene—a genomic sequence similar to the protein-coding MAS1 proto-oncogene-like gene but lacking the ability to produce a functional protein due to disabling mutations. Pseudogenes like MAS1LP1 may be transcribed into RNA and potentially regulate gene expression at the post-transcriptional level, for example by producing antisense RNAs or small interfering RNAs that modulate the activity of related genes. MAS1LP1 itself does not encode a receptor, enzyme, or transporter, and there is currently no direct evidence for its involvement in therapeutic modulation or drug interaction. However, pseudogenes, in general, can influence disease biology and may act as a biomarkers or regulators in conditions such as cancer. MAS1 oncogene and MAS1 proto-oncogene-like are the protein-coding relatives, but MAS1LP1 is not itself a protein-coding therapeutic target and should not be confused with its parental gene MAS1L. If you require structured information on a protein-coding receptor, refer to MAS1L (MAS1 proto-oncogene-like, G protein-coupled receptor). MAS1LP1 (the pseudogene) does not function as a canonical receptor, enzyme, transporter, or therapeutic target.

Other names
MAS1LPMAS1 oncogene-like pseudogene 1OTTHUMG00000086553MAS1LP1
02

Biological functions

Possible modulation of parental gene expression via RNA-based mechanisms (such as antisense transcripts or small interfering RNAs)No direct functional protein activity
03

Disease associations

May act as a biomarker or gene expression regulator in diseases (such as cancer)No direct evidence for a pathogenic or therapeutic role
04

Biomarkers

Potential as a gene expression biomarker, but none in clinical use specific to MAS1LP1

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