Mast cell membrane proteins

The term "mast cell membrane proteins" refers collectively to all protein components located in the plasma membrane of mast cells. Mast cells are immune cells critical for allergic reactions, innate and adaptive immune functions, and protection against pathogens. These cells display a wide range of membrane proteins, including receptors (such as FcεRI, c-Kit), adhesion molecules, tetraspanins (e.g., CD9, CD63), and various adaptor proteins important for cellular activation, signal transduction, and interaction with the tissue environment. However, this term lacks specificity and does not refer to a unique molecular entity, limiting its utility as a singular therapeutic target. Key points: - "Mast cell membrane proteins" is not a canonical molecular target but a heterogeneous group. - The term is too broad and non-specific for structured database or drug targeting purposes. - More precise targets—such as "Fc epsilon RI", "c-Kit receptor (CD117)", "CD9", or "LAT"—should be used when describing drug targets or diagnostic markers on mast cells. - If your goal is to map to a target for structured data, you should select one specific mast cell surface protein.

Other names

Mast cell surface proteinsMast cell membrane components