MAT2A pseudogene 1 (MAT2AP1)

MAT2A pseudogene 1 (MAT2AP1) is a predicted pseudogene—an inactive genetic sequence highly homologous to the functional MAT2A gene (which encodes methionine adenosyltransferase 2A, a key enzyme in methionine metabolism). Unlike MAT2A, the pseudogene does not encode a functional protein and is not characterized as a receptor, enzyme, transporter, or other classic therapeutic target. There is no evidence in major databases, published biomedical literature, or drug target platforms that MAT2AP1 has functional protein product, disease relevance, or serves as a drug target. MAT2AP1 is not a protein-coding gene or valid drug target. The confusion likely arises from conflating the pseudogene (MAT2AP1) with the functional, protein-coding methionine adenosyltransferase 2A gene (MAT2A), which is an important metabolic enzyme with established roles in cellular methylation and potential roles in cancer biology[3][1]. The correct drug target is MAT2A, not MAT2AP1. If you are interested in methionine metabolism, methylation, or relevant drug targets, you should focus on **MAT2A (Methionine adenosyltransferase 2A)**, not the pseudogene MAT2AP1[1][2][3]. Summary: MAT2AP1 is a pseudogene with no evidence of being a functional therapeutic target. Information about its biological role, involvement in disease, or drug interactions is lacking or not applicable. If you meant MAT2A, that target is well-characterized and therapeutically relevant[1][2][3].

Other names

MAT2AP1Methionine adenosyltransferase II, alpha pseudogene 1