Matrin-3 pseudogene (None standard; sometimes LOC401957 in genomic databases)

The *matrin 3 pseudogene* (ENSG00000232952, also known as LOC401957) is a non-functional genomic sequence that resembles the *matrin-3* gene. Pseudogenes arise from gene duplication or retrotransposition but have accumulated mutations that prevent them from encoding a functional protein. Unlike the functional *matrin-3* gene—which is involved in RNA and DNA binding, alternative splicing, and is associated with diseases such as amyotrophic lateral sclerosis—the matrin 3 pseudogene does not produce an active protein and has no established biological function, therapeutic relevance, or disease association. Its presence is mainly cataloged in genomic databases for reference purposes. Key Point: If your focus is therapeutic targeting or disease role, be sure not to confuse the matrin 3 pseudogene with the functional gene (*MATR3*), which is a genuine research and therapeutic interest. The pseudogene itself is not considered a therapeutic target and holds no known biomedical importance.

Other names

LOC401957matrin 3 pseudogene

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