MDH1 pseudogene 1 (MDH1P1)

MDH1 pseudogene 1 (MDH1P1) is a human pseudogene related to the protein-coding gene *Malate dehydrogenase 1 (MDH1)*, which encodes a cytosolic enzyme important in the malate-aspartate shuttle and cellular metabolism. MDH1P1 does *not* encode a functional protein, and there is no evidence that it produces a biologically active product or serves as a direct therapeutic target. Pseudogenes such as MDH1P1 may be used as genomic landmarks but generally do not have functional relevance in cell signaling, disease, or therapy. Functional activity should not be confused with MDH1, which is a true enzyme involved in energy metabolism[1][5][3]. - If you intended to refer to the functional enzyme, see: **Malate dehydrogenase 1 (abbreviation: MDH1)**, which is a key enzyme in energy metabolism and *is* a viable research and therapeutic target[1][3][5]. - The canonical target **MDH1** is not the same as **MDH1P1**; the latter is a non-coding pseudogene. In summary: MDH1P1 is a pseudogene, not a protein-coding gene or druggable target, so it should *not* be considered a canonical or correct entry for most therapeutic, enzymatic, or receptor databases[1][3][5].

Other names

MDH1P1malate dehydrogenase 1 pseudogene 1