Target intelligence / Profile preview

Measles virus F Glycoprotein (F protein)

Target
F protein
Molecular classification
Type I transmembrane glycoprotein
01

Overview

The Measles virus F glycoprotein (Fusion protein) is a critical envelope protein of the measles virus. It mediates the fusion of viral and host cell membranes, enabling viral entry and infection. The functional form on the virion surface is a homotrimer and structural rearrangements are required for membrane fusion. It is considered the first critical step for measles virus infection.

Other names
Fusion proteinMV-F
02

Mechanism of action

Inhibition of membrane fusion

03

Biological functions

Membrane fusionViral entryCell-cell fusion
04

Disease associations

Infection

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