Mechanical aortic valve prosthesis

Mechanical aortic valve prostheses are artificial valves constructed from durable materials (including metals and pyrolytic carbon) that are surgically implanted to replace diseased native aortic valves. They are used to treat severe aortic valve stenosis or regurgitation. Mechanical valves function by mimicking the unidirectional blood flow properties of the native valve, offering superior durability compared to tissue (bioprosthetic) valves but requiring lifelong anticoagulation therapy to prevent thromboembolism. Replacement can be done via open-heart surgery or through less invasive methods like transcatheter aortic valve replacement (TAVR). While these devices restore native valve function mechanically, they are not molecular, protein, or receptor targets and do not directly participate in biological signaling or metabolic pathways.

Other names

Mechanical aortic valvemechanical heart valve prosthesismechanical valve replacement

Mechanical obstruction to backward flow; physically replaces damaged/defective aortic valve to restore function