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Mechanical fixation of prosthesis to living bone refers to the various methods, hardware, and biomechanical strategies used to anchor artificial implants—such as joint replacements or fracture fixation devices—directly to patient bone. This includes the insertion of screws, plates, rods, or cemented and cementless (biological/osseointegrated) joint components. The goal is to provide initial stability and allow either permanent mechanical anchorage or facilitate biological integration of the implant, reducing micromotion, and enabling long-term functional load transfer. Challenges include ensuring fixation strength, promoting bone healing or ongrowth, and avoiding device breakdown, loosening, or infection.
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