Target intelligence / Profile preview

Mechanical fixation of prosthesis to living bone

01

Overview

Mechanical fixation of prosthesis to living bone refers to the various methods, hardware, and biomechanical strategies used to anchor artificial implants—such as joint replacements or fracture fixation devices—directly to patient bone. This includes the insertion of screws, plates, rods, or cemented and cementless (biological/osseointegrated) joint components. The goal is to provide initial stability and allow either permanent mechanical anchorage or facilitate biological integration of the implant, reducing micromotion, and enabling long-term functional load transfer. Challenges include ensuring fixation strength, promoting bone healing or ongrowth, and avoiding device breakdown, loosening, or infection.

Other names
Mechanical fixationProsthetic fixationProsthesis-bone fixationInternal fixation
02

Safety considerations

Device failure (breakdown or loosening of the fixation)infection riskfracture at the bone-implant interfacetissue reaction or osteolysis

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