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Mediator complex subunit 15 pseudogene 1 (MED15P1) is a pseudogene derived from the gene encoding the mediator complex subunit 15, but contains mutations or sequence features preventing production of a functional protein[2][3]. Pseudogenes like MED15P1 are nonfunctional sequences that resemble protein-coding genes; by definition, they do not encode active proteins due to disabling mutations (such as frameshifts or premature stop codons)[3]. Although some pseudogenes can have regulatory roles—such as acting as decoys for microRNAs or influencing the expression of their parent gene—there is no evidence that MED15P1 has a defined functional or regulatory role, nor is it recognized as a therapeutic target[1][3]. On standard genomic databases, its aliases include MED15P and PCQAPP, but functional annotations are lacking[2]. MED15P1 is not a functional therapeutic target; rather, it is a non-coding pseudogene with no evidence for a direct role in disease or as a drug target. Its inclusion as a receptor or enzyme would be incorrect.
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