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Melanin Transmission

Molecular classification: Cellular process, Pigmentation pathway

Overview

Melanin transmission refers to the biological process by which melanin pigment is transferred from melanocytes (the cells that produce melanin) to keratinocytes (the predominant cell type in the outer layer of the skin), resulting in visible pigmentation. It involves the transport of melanosomes from melanocytes to keratinocytes via mechanisms such as exocytosis-endocytosis. The primary function is photoprotection—absorbing harmful UV radiation.

Other names: Melanosome transferPigment transferMelanin transfer

Biological functions

PhotoprotectionSkin pigmentationUV radiation absorptionMelanosome transport

Disease associations

Skin cancerPigmentation disorders (e.g., vitiligo, albinism)Neurodegenerative diseases (related to neuromelanin)Sun sensitivity

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