Target intelligence / Profile preview

Cell Membrane Integrity (None)

Target
None
Molecular classification
Lipid bilayer, Cellular barrier, Structural component
01

Overview

Cell membrane integrity refers to the maintenance of the cell membrane’s structure and function, ensuring it remains a continuous, selectively permeable barrier that separates the cell’s interior from its external environment. This integrity is essential for cellular viability, as it prevents leakage of cellular contents and protects against harmful substances entering the cell. Disruption or impairment in maintaining plasma/cell membrane integrity underlies various diseases. Defective resistance or repair capacity due either to genetic factors or environmental stressors can initiate/progress disease states by compromising tissue structure/functionality.

Other names
Plasma membrane integrityMembrane permeability
02

Biological functions

Selective permeabilitySignal transductionTransportCell adhesionStructural supportProtectionHomeostasis
03

Disease associations

Muscular dystrophyCystic fibrosisInfectious diseasesTraumatic injuriesInflammatory bowel diseaseCancerNeurodegenerative diseaseCardiovascular diseaseInfection

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