Membrane-spanning 4-domains subfamily A member 5 (MS4A5)

Membrane-spanning 4-domains subfamily A member 5 (MS4A5) is a protein encoded by the MS4A5 gene, located on chromosome 11q12, and is a member of the membrane-spanning 4A gene family[1][2][5]. Members of this family share structural features—four transmembrane domains resembling tetraspanins—and likely participate in multimeric membrane complexes that can be involved in signal transduction processes[5][1]. While some MS4A family members have well-characterized roles (such as MS4A1/CD20 in B cells), MS4A5 is not expressed in hematopoietic cells specifically and its precise function remains unclear, though it may be involved in signaling like related proteins[1][2][5]. This gene does not currently have documented direct links to drug interactions, therapeutic targeting, or use as a biomarker.

Other names

CD20-L2CD20L2TETM4Testis-expressed transmembrane protein 4Testis-expressed transmembrane-4 proteinCD20 antigen-like 2