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Membrane-spanning 4-domains subfamily A member 6E (MS4A6E)
- Target
- MS4A6E
- Molecular classification
- Other (member of the membrane-spanning 4A (MS4A) protein family, which are tetraspanning or "tetraspan" membrane proteins[2][5][8])
01
Overview
Membrane-spanning 4-domains subfamily A member 6E (MS4A6E) is a protein-coding gene and a member of the MS4A family, characterized by four transmembrane domains and grouped in a gene cluster on chromosome 11q12.3[1][2][5]. It may function in signal transduction as part of multimeric receptor complexes, though its physiological role remains unconfirmed and its tissue expression appears restricted as compared to other MS4A family members[2][3][8]. Diseases associated with MS4A6E include Froelich Syndrome and Basophil Adenoma, but it is not established as a direct therapeutic target or widely recognized disease biomarker[2][3][6][8].
- Other names
- MS4A6EMembrane spanning 4-domains A6EMembrane-spanning 4-domains subfamily A member 6E
02
Biological functions
Likely signal transduction as a component of a multimeric receptor complex[2][8]Unique/unknown tissue-specific functions (expression patterns differ distinctly from other MS4A family proteins[3])
03
Disease associations
Other (Genetic link with Froelich Syndrome and Basophil Adenoma; not established as a driver in major human disease classes)[2]
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