Target intelligence / Profile preview

Menstrual cycle regulation

Molecular classification
Other (physiological process)
01

Overview

"Menstrual cycle regulation" is the coordination of hormonal and physiological interactions among the hypothalamus, anterior pituitary gland, ovaries, and uterus that control the cyclic process of ovulation and endometrial shedding in females. This regulation involves the release of gonadotropin-releasing hormone (GnRH) from the hypothalamus, stimulating the pituitary secretion of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which then prompt the ovaries to produce estrogen and progesterone. These sex steroids direct the growth and regression of the endometrial lining and modulate the feedback to the brain to maintain cyclicity[1][2][4][5][6][7]. Disruptions to these regulatory pathways can lead to a variety of menstrual disorders. For molecular-level drug targeting, the appropriate entities would be: - Gonadotropin-releasing hormone receptor - Follicle-stimulating hormone receptor - Luteinizing hormone receptor - Estrogen receptor - Progesterone receptor "Menstrual cycle regulation" should not be used as a molecular target entry.

Other names
Menstrual cycleRegulation of menstruationCycle control
02

Biological functions

Reproductive cycle coordinationOvulation controlEndometrial regenerationHormonal homeostasis
03

Disease associations

Other (disease associations include disorders of menstruation such as amenorrhea, dysmenorrhea, premenstrual syndrome, but "menstrual cycle regulation" itself is not a disease role.)

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