Mesalamine dissolution and release from pH-dependent formulations

"Mesalamine dissolution and release from pH-dependent formulations" does **not** refer to a specific molecule, protein target, receptor, enzyme, or transporter. Instead, it describes a pharmaceutical technology designed for the targeted oral delivery of mesalamine (also known as mesalazine or 5-amino­salicylic acid) using coatings that dissolve at specific gastrointestinal tract pH values. These formulations use polymers such as Eudragit L or S to ensure that mesalamine is released only when the surrounding environment reaches a certain pH—typically in the terminal ileum or colon—thereby maximizing local therapeutic effect while minimizing systemic absorption and upper GI side effects[1][2][3][4][5]. The "target" here is *not* a biological entity but rather refers to controlled-release characteristics engineered into dosage forms. This entry should be flagged as incorrect for molecular target databases because it does **not** represent an actual therapeutic target such as a receptor or enzyme; instead it describes properties of pharmaceutical dosage forms.

Other names

Mesalamine pH-dependent formulationMesalazine pH-dependent release5-aminosalicylic acid (5-ASA) pH-dependent delivery system