Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Mesenchymal Stromal Cell (MSC)
- Target
- MSC
- Molecular classification
- Stromal cell, Multipotent cell
01
Overview
Mesenchymal stromal cells (MSCs) are multipotent stromal cells capable of differentiating into a variety of cell types, including osteoblasts, chondrocytes, myocytes, and adipocytes. They are characterized by their ability to modulate inflammation, facilitate tissue repair and regeneration through secretion of bioactive molecules and extracellular vesicles, and exert immunomodulatory effects. MSCs are being investigated extensively for regenerative medicine applications.
- Other names
- Mesenchymal stem cellMedicinal signaling cellcellula mesenchymatica praecursoria
02
Mechanism of action
Paracrine signaling via secretion of bioactive molecules and extracellular vesicles, direct cell contact
03
Biological functions
Tissue repairTissue regenerationImmunomodulationExtracellular matrix productionAngiogenesisNeurogenesis
04
Disease associations
Graft-versus-host diseaseMyocardial infarctionWound healingBone defectsCartilage defectsAutoimmune diseases
05
Safety considerations
Heterogeneity of MSC populationsVariable efficacy in clinical trialsPotential for off-target effectsLong-term safety unknown
06
Biomarkers
CD105+CD73+CD90+CD45-CD34-CD14-CD19-CD3-HLA DR-
Beyond the preview
Go deeper on Mesenchymal Stromal Cell (MSC).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Mesenchymal Stromal Cell (MSC).