Mesoderm specific transcript pseudogene 2 (MESTP2)

Mesoderm specific transcript pseudogene 2 (MESTP2) is classified as a pseudogene in the human genome, located on chromosome 6. As a pseudogene, MESTP2 is a nonfunctional DNA segment that resembles the active mesoderm specific transcript (MEST) gene, but lacks the necessary elements to produce a functional protein or participate in normal gene regulatory functions. To date, there is no evidence that MESTP2 is implicated in disease, biological function, or drug interactions. MESTP2 is not a known therapeutic target, receptor, enzyme, transporter, or signaling molecule. There may be confusion with the "Mesoderm specific transcript" (MEST) gene, which is protein-coding, involved in development and imprinting, and possibly implicated in cancer and related diseases. MESTP2, however, is a nonfunctional paralog with no evidence of functional transcripts or protein. No known aliases or alternative names for MESTP2 are listed in main gene/protein databases. Pseudogenes like MESTP2 may be transcribed at low levels, but these transcripts usually have no known function and are not considered biologically active. If you are seeking a target for therapeutic, diagnostic, or biomarker purposes, MESTP2 is not valid—consider the parent functional gene MEST instead.