Mesoderm specific transcript pseudogene 3 (MESTP3)

Mesoderm specific transcript pseudogene 3 (MESTP3) is a member of the broad class of pseudogenes in the human genome. Pseudogenes are genomic DNA sequences similar to normal genes but are typically nonfunctional; they arise due to duplication or retrotransposition events followed by sequence decay[4]. Although some pseudogenes can exert regulatory roles—for instance, by acting as decoys for microRNAs or influencing gene expression—there is no evidence that MESTP3 has any specific biological or disease-related function. It should be distinguished from the functional mesoderm specific transcript gene (MEST), which is an imprinted gene encoding a protein implicated in adipose tissue biology and other functions in mice[3][5]. MESTP3 itself does not encode a receptor, enzyme, or other protein relevant for pharmacological targeting or disease association[1]. Note: If your focus is on drug discovery or functional genomics, MESTP3 is not a valid molecular target and should not be confused with the protein-coding MEST gene. No information exists for therapeutic modulation, safety issues, or clinical relevance for MESTP3[1][5].

Other names

mesoderm specific transcript homolog pseudogene 3MESTP3

None defined. As MESTP3 is a pseudogene and not known to encode a functional protein, there is no mechanism of action relevant to this molecule[1]