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Target intelligence / Profile preview
Messenger RNA (mRNA)
- Target
- mRNA
- Molecular classification
- RNA, Non-coding RNA
01
Overview
Messenger RNA (mRNA) is a single-stranded RNA molecule transcribed from DNA that carries genetic instructions from the cell nucleus to the cytoplasm, where it serves as a template for protein synthesis by ribosomes. In eukaryotes, mature mRNAs have a 5' cap and a 3' poly-A tail. Synthetic mRNAs are used therapeutically as vaccines or gene therapies.
02
Mechanism of action
Synthetic mRNAs are translated into proteins within cells, eliciting a therapeutic effect or immune response.
03
Biological functions
Template for protein synthesisCarries genetic information from DNA to ribosome
04
Disease associations
CancerInfectionOther (potential target for mRNA-based therapies and vaccines)
05
Safety considerations
Potential for off-target effects with mRNA-based therapiesImmune responses to synthetic mRNA
06
Interacting drugs
Synthetic mRNAs (vaccines, gene therapies)
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