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The term "metabolic and endothelial pathways" refers to a collection of interconnected metabolic routes that govern endothelial cell function, including glycolysis, fatty acid oxidation, glutamine metabolism, and the regulation of redox balance[1][2][3][4]. These pathways are critical for endothelial cell proliferation, angiogenesis, and the maintenance of vascular health. Perturbations in these pathways are involved in a variety of diseases, including cardiovascular disorders, diabetes, and cancer. However, "metabolic and endothelial pathways" is not a specific molecular target but rather describes the coordinated metabolic processes within endothelial cells that can themselves be regulated by several individual molecules and enzymes such as PFKFB3, CPT1a, and GLS1[1][2][3][4].
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